CBD guide

  • Introduction

    Cannabis is a plant that provides numerous valuable active ingredients. The most important

    include phytocannabinoids, flavonoids and terpenes.

    Through the growing experience and awareness of the diverse effects of these

    Plant for various complaints, the medical-scientific

    Research has been intensified considerably, and a system of the body’s own was discovered that enables

    active substances contained in cannabis – the so-called endocannabinoid

    System. This extremely complex system consists of receptors, the body’s own

    Cannabinoids (endocannabinoids) and enzymes responsible for their formation and degradation

    are responsible.

    The activation of these receptors by endocannabinoids contributes significantly to the

    to maintain balance (homeostasis) in the body.

  • Mechanisms of action

    Scientific studies have shown that the above-mentioned active ingredients – individually or

    in interaction as a phytocomplex – both physiological and pathophysiological

    can influence processes in two ways:

    1. By directly binding to cannabinoid receptors
    2. Through the so-called entourage effect, in which the binding affinity

    endocannabinoids to their receptors and their degradation

    is slowed down

    What are phytocannabinoids? → Plant molecules.

    What are endocannabinoids? → Molecules that our body produces itself.

    The receptors responsible for processing phytocannabinoids are called

    CB1 and CB2. These receptors help to break down the molecules and trigger processes

    through which our body produces its own endocannabinoids – important substances that

    contribute significantly to maintaining homeostasis.

Homeostasis – what does it mean?

Homeostasis describes the ability of living organisms to maintain their internal conditions stable

to maintain this even when external circumstances change. This shows how important this

System is also for the immune system.

It has been found that endocannabinoids not only bind to CB1 and CB2 receptors

bind, but also interact with serotonin and vanilloid receptors, which are particularly

play a role in pain regulation.

Here is a brief overview of the effects of phytocannabinoids on various

Body systems:

• Central nervous system: anticonvulsant, appetite stimulant, anti-nausea,

pain-relieving

• Cardiovascular system: vasodilator, can increase pulse rate

• Respiratory system: bronchodilator

• Visual organ: Reduction of intraocular pressure

• Immune system: Strengthening the body’s defenses

  • Interesting fact

    The brain stem, which controls vital functions such as heartbeat and breathing, is

    almost free of CB1 and CB2 receptors. This explains why there are no lethal

    Overdoses due to acute cannabis poisoning. In contrast, these

    However, receptors are abundant in the spinal cord and parts of the brain that are responsible for

    are responsible for regulating pain and inflammatory processes.

    In summary, phytocannabinoids have a variety of positive effects in

    body – antioxidant, antihypertensive, anti-inflammatory,

    pain-relieving and immune-boosting. The presence of CB1 and CB2 receptors in

    different brain regions also indicates important functions in sleep, appetite,

    learning processes, emotional states and a possible neuroprotective effect

    there.

    Of particular interest is the role of this system in controlling the growth of

    Tumor cells.

  • What is a phytocomplex?

    A phytocomplex refers to the totality of all chemical components of a plant,

    which together are responsible for their specific therapeutic effects.

    The cannabis plant has a phytocomplex of around 800 different

    molecules. The most well-known of these are:

    • Cannabinoids: aromatic hydrocarbons with oxygen compounds, among

    including CBG, CBC, CBD, THC, CBN, CBL, CBE, CBT• Terpenes: Main components of plant resins that are responsible for taste and fragrance

    responsible; chemically aromatic organic hydrocarbons, e.g.

    Limonene, Pinene, Myrcene, Caryophyllene, Linalool

    • Flavonoids: aromatic polyphenols, known for their antioxidant properties,

    which are increasingly receiving attention in nutrition and medicine

  • Advantages and possible areas of application

    • Neuroprotective: helps reduce oxidative stress in brain cells
    • Effective in chronic inflammatory bowel diseases
    • Antibacterial: works against resistant bacteria and can have an antibiotic effect
    • Regulates the immune system: Phytocannabinoids directly intervene in immunological processes
    • Antiemetic: helps against nausea and vomiting
    • Effective for conditions such as high blood pressure, fibromyalgia, muscle cramps
    • Vasodilator: can increase the diameter of blood vessels and thus lower blood pressure
    • Inhibits the growth of tumor cells
    • Anxiety-relieving: has a calming effect on anxiety and stress
    • Pain relieving: modulates pain perception
    • Blood sugar lowering: reduces and stabilizes the glucose level in the blood
    • Promotes bone growth
    • Anticonvulsant: can prevent or reduce epileptic seizures
    • Anti-inflammatory: works against various forms of inflammation
    • Bronchodilator: facilitates breathing by widening the airways

  • Methods for extracting cannabinoids and terpenes

    There are different processes to extract cannabinoids and terpenes and for the

    Production of oils, creams, capsules or crystals, including:

    • Supercritical CO₂ extraction (also used for decaffeinating coffee)
    • Subcritical CO₂ extraction
    • Extraction with ethanol
    • Extraction with hydrocarbons
    • Ultrasonic extraction
    • Cold pressing under high pressure
    • Extraction using sonicators

    To produce a high quality CBD oil, it is crucial to pay attention to both the

    Attention must be paid to both the starting material and the process. For this reason

    Beleaf uses only organic flowers and gentle processes such as

    Cold pressing under high pressure produces a stable oil rich in cannabinoids,

    terpenes and flavonoids. For the extraction of pure CBD molecules,

    Ultrasonic extraction is used, which ensures safe processing and high

    Yield guaranteed.

    CBD oils are available in different concentrations to suit individual

    to meet the needs of different users.

  • Neuropathic pain

    There is evidence that the endocannabinoid system plays a crucial role in

    regulation of neuropathic pain. It acts through mechanisms that

    Influence pain transmission at the neuronal level.

    Anxiety disorders

    Cannabidiol has promising therapeutic properties in neuropsychiatric

    Its effects on the central nervous system have led it to

    In recent years it has become an exciting research subject as a possible remedy against anxiety

    and stressed.

  • skin system

    The density of CB1 and CB2 receptors in the skin, epidermis and dermis is

    remarkable. CBD supports the renewal and antioxidant activity of older

    skin cells and promotes the formation of new cells. There are also positive results in

    Treatment of certain autoimmune diseases. In the co